1. The intricate mechanisms of neurodegeneration in prion diseases Author(s): Soto C, Satani N Source: TRENDS IN MOLECULAR MEDICINE Volume: 17 Issue: 1 Pages: 14-24 Published: JAN 2011
2. Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress Author(s): Torres M, Castillo K, Armisen R, et al. Source: PLOS ONE Volume: 5 Issue: 12 Article Number: e15658 Published: DEC 29 2010
3. The role of calcium ions in the interactions of PrP106-126 amide with model membranes Author(s): Zhong J, Yang CH, Zheng WF, et al. Source: COLLOIDS AND SURFACES B-BIOINTERFACES Volume: 77 Issue: 1 Pages: 40-46 Published: MAY 1 2010
4. Role of GFAP in morphological retention and distribution of reactive astrocytes induced by scrapie encephalopathy in mice Author(s): Gomi H, Yokoyama T, Itohara S Source: BRAIN RESEARCH Volume: 1312 Pages: 156-167 Published: FEB 2 2010
5. Neuroinflammation in Prion Diseases: Concepts and Targets for Therapeutic Intervention Author(s): Riemer C, Gultner S, Heise I, et al. Source: CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS Volume: 8 Issue: 5 Pages: 329-341 Published: NOV 2009
6. Title: Accelerated Prion Replication in, but Prolonged Survival Times of, Prion-Infected CXCR3(-/-) Mice Author(s): Riemer C, Schultz J, Burwinkel M, et al. Source: JOURNAL OF VIROLOGY Volume: 82 Issue: 24 Pages: 12464-12471 Published: DEC 15 2008
7. Thellung S, Villa V, Corsaro A, et al. ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation GLIA 55 (14): 1469-1485 NOV 1 2007
8. Choi CJ, Anantharam V, Saetveit NJ, et al. Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death TOXICOLOGICAL SCIENCES 98 (2): 495-509 AUG 2007
9. Thellung S, Corsaro A, Villa V, et al. Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1096: 258-270 2007
10. Fioriti L, Angeretti N, Colombo L, et al. Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Straussler-Scheinker disease amyloid protein JOURNAL OF NEUROSCIENCE 27 (7): 1576-1583 FEB 14 2007
11. Hou X, Parkington HC, Coleman HA, et al. Transthyretin oligomers induce calcium influx via voltage-gated calcium channels JOURNAL OF NEUROCHEMISTRY 100 (2): 446-457 JAN 2007
12. Kosugi T, Kawahara K Reversed actrocytic GLT-1 during ischemia is crucial to excitotoxic death of neurons, but contributes to the survival of astrocytes themselves NEUROCHEMICAL RESEARCH 31 (7): 933-943 JUL 2006
13. Gray BC, Skipp P, O'Connor VM, et al. Increased expression of glial fibrillary acidic protein fragments and mu-calpain activation within the hippocampus of prion-infected mice BIOCHEMICAL SOCIETY TRANSACTIONS 34: 51-54 Part 1 FEB 2006
14. Re L, Rossini F, Re F, et al. Prion protein potentiates acetylcholine release at the neuromuscular junction PHARMACOL RES 53 (1): 62-68 JAN 2006
15. Shamsir MS, Dalby AR One gene, two diseases and three conformations: Molecular dynamics simulations of mutants of human prion protein at room temperature and elevated temperatures PROTEINS 59 (2): 275-290 MAY 1 2005
16. Corsaro A, Thellung S, Villa V, et al. Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation ANN NY ACAD SCI 1010: 610-622 2003
17. Sassoon J, Daniels M, Brown DR Astrocytic regulation of NMDA receptor subunit composition modulates the toxicity of prion peptide PrP106-126 MOL CELL NEUROSCI 25 (1): 181-191 JAN 2004
18. Farrelly PV, Kenna BL, Laohachai KL, et al. Quinacrine blocks PrP (106-126)-formed channels J NEUROSCI RES 74 (6): 934-941 DEC 15 2003
19. Berest V, Rutkowski M, Rolka K, et al. The prion peptide forms ion channels in planar lipid bilayers CELL MOL BIOL LETT 8 (2): 353-362 2003
20. Kourie JI, Kenna BL, Tew D, et al. Copper modulation of ion channels of PrP[106-126] mutant prion peptide fragments J MEMBRANE BIOL 193 (1): 35-45 MAY 1 2003
21. Florio T, Paludi D, Villa V, et al. Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic J NEUROCHEM 85 (1): 62-72 APR 2003
22. Hur K, Kim JI, Choi SI, et al. The pathogenic mechanisms of prion diseases MECH AGEING DEV 123 (12): 1637-1647 NOV 2002
23. Kourie JI  Prion channel proteins and their role in vacuolation and neurodegenerative diseases EUR BIOPHYS J BIOPHY 31 (5): 409-416 SEP 2002
24. Kourie JI, Culverson AL, Farrelly PV, et al. Heterogeneous amyloid-formed ion channels as a common cytotoxic mechanism - Implications for therapeutic strategies against amyloidosis CELL BIOCHEM BIOPHYS 36 (2-3): 191-207 2002
25. Brown DR Mayhem of the multiple mechanisms: modelling neurodegeneration in prion diseaseJ NEUROCHEM 82 (2): 209-215 JUL 2002
26. Corsaro A, Thellung S, Russo C, et al. Expression in E-coli and purification of recombinant fragments of wild type and mutant human prion protein NEUROCHEM INT 41 (1): 55-63 JUL 2002
27. Milhavet O, Lehmann S  Oxidative stress and the prion protein in transmissible spongiform encephalopathies BRAIN RES REV 38 (3): 328-339 FEB 2002
28. Thellung S, Villa V, Corsaro A, et al. p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells NEUROBIOL DIS 9: (1) 69-81 FEB 2002
29. Kourie JI Mechanisms of prion-induced modifications in membrane transport properties: Implications for signal transduction and neurotoxicity CHEM-BIOL INTERACT 138: (1) 1-26 OCT 25 2001
30. Kourie JI, Farrelly PV, Henry CL Channel activity of deamidated isoforms of prion protein fragment 106-126 in planar lipid bilayers J NEUROSCI RES 66: (2) 214-220 OCT 15 2001
31. Tagliavini F, Forloni G, D'Ursi P, et al. Studies on peptide fragments of prion proteins ADV PROTEIN CHEM 57: 171-+ 2001
32. Bajetto A, Barbero S, Bonavia R, et al.Stromal cell-derived factor-1 alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway. J NEUROCHEM 77: (5) 1226-1236 JUN 2001
33. Smith JP, Cunningham LA, Partridge LD Coupling of AMPA receptors with the Na+/Ca2+ exchanger in cultured rat astrocytes BRAIN RES 887: (1) 98-109 DEC 22 2000
34. Kourie JI, Culverson A Prion peptide fragment PrP[106-126] forms distinct cation channel types J NEUROSCI RES 62: (1) 120-133 OCT 1 2000
35. Muller WEG, Laplanche JL, Ushijima H, et al. Novel approaches in diagnosis and therapy of Creutzfeldt-Jakob disease MECH AGEING DEV 116: (2-3) 193-218 JUL 31 2000
36. Herms JW, Korte S, Gall S, et al. Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice J NEUROCHEM 75: (4) 1487-1492 OCT 2000
37. Thellung S, Florio T, Villa V, et al. Apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126 NEUROBIOL DIS 7: (4) 299-309 AUG 2000
38. Kourie JI, Shorthouse AA Properties of cytotoxic peptide-formed ion channels AM J PHYSIOL-CELL PH 278: (6) C1063-C1087 JUN 2000
39. Thellung S, Florio T, Corsaro A, et al. Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126. INT J DEV NEUROSCI 18: (4-5) 481-492 JUL-AUG 2000
40. Silei V, Fabrizi C, Venturini G, et al. Measurement of intracellular calcium levels by the fluorescent Ca2+ indicator Calcium-Green BRAIN RES PROTOC 5: (2) 132-134 APR
41. Kim JI, Ju WK, Choi JH, et al. Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice
    MOL BRAIN RES 73: (1-2) 17-27 NOV 10 1999
42. White AR, Collins SJ, Maher F, et al.  Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicityAM J PATHOL 155: (5) 1723-1730 NOV 1999
43. Florio T, Thellung S, Arena S, et al.  Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro EUR J ENDOCRINOL 141: (4) 396-408 OCT 1999
44. Grimaldi M, Cavallaro S Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes EUROPEAN JOURNAL OF NEUROSCIENCE 11: (8) 2767-2772 AUG 1999
45. Thellung S, Florio T, Maragliano A, Cattarini G, Schettini G Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: Involvement of A(2) purinergic receptor subtypes LIFE SCIENCES 64: (18) 1661-1674 MAR 26 1999
46. Salmona M, Bugiani O, Tagliavini F, Lauro GM Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels Silei V, Fabrizi C, Venturini G, BRAIN RESEARCH 818: (1) 168-170 FEB 6 1999
47. Colin K. Combs, Derrick E. Johnson, Steve B. Cannady, Timothy M. Lehman, and Gary E. Landreth. Identification of Microglial Signal Transduction Pathways Mediating a Neurotoxic Response to Amyloidogenic Fragments of -Amyloid and PrionProteins The Journal of Neuroscience, February 1, 1999, 19(3):928-939
48. Florio T, Thellung S, Amico C, Robello M, Salmona M, Bugiani O, Tagliavini F, Forloni G, Schettini G Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line JOURNAL OF NEUROSCIENCE RESEARCH 54: (3) 341-352 NOV 1 1998
49. Brown DR, Schmidt B, Kretzschmar HA A prion protein fragment primes type 1 astrocytes to proliferation signals from microglia NEUROBIOL DIS 4: (6) 410-422 APR 1998
50. Verkhratsky A, Orkand RK, Kettenmann H Glial calcium: Homeostasis and signaling function PHYSIOL REV 78: (1) 99-141 JAN 1998
51. Aguzzi A, Weissmann C Prion diseases HAEMOPHILIA 4: (4) 619-627 JUL 1998
52. Salmona M, Forloni G, Diomede L, et al. A neurotoxic and gliotrophic fragment of the prion protein increases plasma membrane microviscosity NEUROBIOL DIS 4: (1) 47-57 1997